• Automated segmentation of magnetic resonance bone marrow signal: a feasibility study 

      von Brandis, Elisabeth; Jenssen, Håvard Bjørke; Avenarius, Derk Frederik Matthaus; Bjørnerud, Atle; Flatø, Berit; Tomterstad, Anders; Lilleby, Vibke; Rosendahl, Karen; Sakinis, Tomas; Zadig, Pia Karin Karlsen; Müller, Lil-Sofie Ording (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-02)
      Background - Manual assessment of bone marrow signal is time-consuming and requires meticulous standardisation to secure adequate precision of findings.<p> <p>Objective - We examined the feasibility of using deep learning for automated segmentation of bone marrow signal in children and adolescents.<p> <p>Materials and methods - We selected knee images from 95 whole-body MRI examinations of ...
    • Erosion or normal variant? 4-year MRI follow-up of the wrists in healthy children 

      Avenarius, Derk; Müller, Lil-Sofie Ording; Rosendahl, Karen (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-12-04)
      Background A large proportion of healthy children have wrist changes on MRI, namely carpal depressions, findings that have been described as pathological in children with juvenile idiopathic arthritis.<p> <p>Objective We performed follow-up imaging in a cohort of healthy children to evaluate carpal surface depressions over time, focusing on the presence of overlying cartilage as a potential ...
    • Establishment of normative MRI standards for the paediatric skeleton to better outline pathology Focused on juvenile idiopathic arthritis 

      Müller, Lil-Sofie Ording (Doctoral thesis; Doktorgradsavhandling, 2012-10-19)
      Prosjektet har som formål å kartlegge normalfunn ved ulike MR-undersøkelser som brukes ved diagnostikk og oppfølging av barn med barneleddgikt og andre skjelettlidelser. Når man utvikler følsomme metoder for å oppdage sykdom er det viktig å finne ut om de også er nøyaktige. 88 barn fra 5-15 år ble undersøkt med MR og røntgen av håndleddet. 44 barn fikk i tillegg utført en spesial sekvens av ryggen. ...
    • Feil i aldersvurderingen av unge asylsøkere 

      Aarseth, Svein; Sund, Torbjørn; Müller, Lil-Sofie Ording; Bring, Johan (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-08)
      Dagens bruk av verktøyet BioAlder for å finne sannsynlig aldersspenn hos asylsøkere er basert på en statistisk feilslutning. Mindreårige risikerer å klassifiseres som voksne.
    • Pediatric whole-body magnetic resonance imaging: comparison of STIR and T2 Dixon sequences in the detection and grading of high signal bone marrow changes 

      Zadig, Pia Karin Karlsen; von Brandis, Elisabeth; Müller, Lil-Sofie Ording; Tanturri De Horatio, Laura; Rosendahl, Karen; Avenarius, Derk Frederik Matthaus (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-26)
      Objectives To compare short time inversion recovery (STIR) and T2 Dixon in the detection and grading of high signal intensity areas in bone marrow on whole-body MRI in healthy children. <p><p>Methods Prospective study, including whole-body 1.5-T MRIs from 77 healthy children. Two experienced radiologists in consensus identifed and graded areas of high bone marrow signal on STIR and T2-weighted (T2W) ...
    • Revisiting the radiographic assessment of osteoporosis-Osteopenia in children 0-2 years of age. A systematic review 

      Rosendahl, Karen; Lundestad, Anette; Bjørlykke, John Asle; Lein, Regina Küfner; Angenete, Oskar W; Augdal, Thomas Angell; Müller, Lil-Sofie Ording; Jaramillo, Diego (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-02)
      <i>Background</i> - Imaging for osteoporosis has two major aims, first, to identify the presence of low bone mass (osteopenia), and second, to quantify bone mass using semiquantitative (conventional radiography) or quantitative (densitometry) methods. In young children, densitometry is hampered by the lack of reference values, and high-quality radiographs still play a role although the evaluation ...
    • Whole body magnetic resonance imaging in healthy children and adolescents. Bone marrow appearances of the axial skeleton 

      von Brandis, Elisabeth; Zadig, Pia Karin Karlsen; Avenarius, Derk Frederik Matthaus; Flatø, Berit; Knudsen, Per Kristian; Lilleby, Vibke; Nguyen, Bac; Rosendahl, Karen; Müller, Lil-Sofie Ording (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-27)
      Objective - To describe the findings of focal high signal on T2 weighted (T2W) images of the bone marrow in the axial skeleton as assessed by whole-body MRI in healthy and asymptomatic children and adolescents.<p> <p>Material and methods - We assessed the bone marrow of the mandible, shoulder girdle, thorax, spine, and pelvis on water-only Dixon T2W sequences as part of a whole-body MRI protocol ...
    • Whole body magnetic resonance imaging in healthy children and adolescents: Bone marrow appearances of the appendicular skeleton 

      Zadig, Pia Karin Karlsen; von Brandis, Elisabeth; Flatø, Berit; Müller, Lil-Sofie Ording; Nordal, Ellen Berit; Tanturri De Horatio, Laura; Rosendahl, Karen; Avenarius, Derk Frederik Matthaus (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-20)
      Objective: To describe the appearances of bone marrow in the appendicular skeleton on fat-suppressed T2- weighted sequences as assessed by whole-body MRI in healthy and asymptomatic children and adolescents.<p> <p>Material and methods: Following ethical approval, we assessed the bone marrow of the extremities on water-only Dixon T2-weighted images as part of a whole-body MRI in 196 healthy and ...
    • Whole-body magnetic resonance imaging in children – how and why? A systematic review 

      Zadig, Pia Karin Karlsen; von Brandis, Elisabeth; Lein, Regina Küfner; Rosendahl, Karen; Avenarius, Derk; Müller, Lil-Sofie Ording (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-25)
      Whole-body magnetic resonance imaging (MRI) is increasingly being used for a number of indications. Our aim was to review and describe indications and scan protocols for diagnostic value of whole-body MRI for multifocal disease in children and adolescents, we conducted a systematic search in Medline, Embase and Cochrane for all published papers until November 2018. Relevant subject headings and free ...
    • Whole-body MRI in children aged 6–18 years. Reliability of identifying and grading high signal intensity changes within bone marrow 

      Zadig, Pia Karin Karlsen; von Brandis, Elisabeth; d’Angelo, Paola; Tanturri de Horatio, Laura; Müller, Lil-Sofie Ording; Rosendahl, Karen; Avenarius, Derk Frederik Matthaus (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-21)
      Background - Whole-body magnetic resonance imaging (MRI) is increasingly being used in children, however, to date there are no studies addressing the reliability of the findings.<p> <p>Objective - To examine intra- and interobserver reliability of a scoring system for assessment of high signal areas within the bone marrow, as visualized on T2-weighted, fat-saturated images.<p> <p>Materials and ...
    • Whole-body MRI in children and adolescents: Can T2-weighted Dixon fat-only images replace standard T1-weighted images in the assessment of bone marrow? 

      Tanturri De Horatio, Laura; Zadig, Pia Karin Karlsen; von Brandis, Elisabeth; Müller, Lil-Sofie Ording; Rosendahl, Karen; Avenarius, Derk Frederik Matthaus (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-08)
      Objective: When performing whole-body MRI for bone marrow assessment in children, optimizing scan time is crucial. The aim was to compare T2 Dixon fat-only and TSE T1-weighted sequences in the assessment of bone marrow high signal areas seen on T2 Dixon water-only in healthy children and adolescents. <p><p>Materials and methods: Whole-body MRIs from 196 healthy children and adolescents aged 6 to 19 ...